Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 81
Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis.
PMID 32762840 · PMC7413667 · eLife · 2020 · 8 claims · 8 setups
mRNA localization to mitochondria is condition-dependent: ATP3 mRNA switches from low (diffuse) association in fermentative conditions to strong mitochondrial association in respiratory conditions, while TIM50 is constitutively localized and TOM22 is diffuse.
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Genomics and proteomics of immune modulatory effects of a butanol fraction of echinacea purpurea in human dendritic cells.
PMID 18847511 · PMC2571112 · BMC genomics · 2008 · 8 claims · 8 setups
[BF/S+L/Ep] butanol fraction from E. purpurea enhances maturation of human immature dendritic cells (increased CD83 expression)
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Proteomic analysis of the mammalian nuclear pore complex.
PMID 12196509 · PMC2173148 · The Journal of cell biology · 2002 · 8 claims · 7 setups
Mass spectrometry was used to identify all proteins present in a biochemically purified rat liver NPC fraction.
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H-DBAS: human-transcriptome database for alternative splicing: update 2010.
PMID 19969536 · PMC2808982 · Nucleic acids research · 2010 · 8 claims · 4 setups
RNA-Seq tags from the polysome fraction identify AS exons that are very likely used for protein synthesis
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Placental proteomics: a shortcut to biological insight.
PMID 19070895 · PMC3532024 · Placenta · 2009 · 7 claims · 5 setups
Developed a novel small cationic colloidal silica (smCCS) method to uniformly enrich the apical plasma membrane of the syncytiotrophoblast (STB) for proteomics analysis
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Has reproduction · 70
MACanalyzeR scRNAseq analysis tool reveals PPARγ(HIGH)/GDF15(HIGH) lipid-associated macrophages facilitate thermogenic expansion in BAT.
PMID 40450001 · PMC12126529 · Nature communications · 2025 · 8 claims · 8 setups
MACanalyzeR is a novel computational scRNAseq framework (with FoamSpotteR, MacPolarizeR, and PathAnalyzeR modules) for comprehensive monocyte/macrophage metabolic and phenotypic profiling
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High frequency of deletions at the hypoxanthine-guanine phosphoribosyltransferase locus in an ataxia-telangiectasia lymphoblastoid cell line irradiated with gamma-rays.
PMID 11714443 · PMC5926665 · Japanese journal of cancer research : Gann · 2001 · 7 claims · 5 setups
A high proportion (12/15, 80%) of gamma-ray-induced HPRT-deficient mutants in A-T (GM2783) cells are deletions
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Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis.
PMID 18802454 · PMC2527686 · PLoS genetics · 2008 · 8 claims · 6 setups
Three heterozygous missense mutations (p.M337V, p.N345K, p.I383V) in exon 6 of TARDBP were identified in familial ALS patients
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Topology of molecular machines of the endoplasmic reticulum: a compilation of proteomics and cytological data.
PMID 18172663 · PMC2228376 · Histochemistry and cell biology · 2008 · 8 claims · 8 setups
Proteomics studies of ER subcompartments provide a protein dictionary revealing that specific molecular machines localize to specific ER subdomains
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Synaptic proteins linked to HIV-1 infection and immunoproteasome induction: proteomic analysis of human synaptosomes.
PMID 19693676 · PMC2824116 · Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2010 · 8 claims · 7 setups
Proteomic screening of human synaptosomes identifies a set of proteins differentially expressed in HIV/AIDS brain
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Long-range regulation is a major driving force in maintaining genome integrity.
PMID 19682388 · PMC2741452 · BMC evolutionary biology · 2009 · 7 claims · 5 setups
Long-range transcriptional regulation is a major driving force in maintaining genome integrity by constraining where chromosomal breakpoints can become fixed.
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A novel gammaD-crystallin mutation causes mild changes in protein properties but leads to congenital coralliform cataract.
PMID 19668596 · PMC2722711 · Molecular vision · 2009 · 8 claims · 6 setups
A novel heterozygous CRYGD mutation c.43C>A (R15S) causes congenital coralliform cataract in Family A
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Contributions of proteomics to understanding phagosome maturation.
PMID 18331591 · PMC2613258 · Cellular microbiology · 2008 · 8 claims · 8 setups
Proteomic studies across many species have identified hundreds of proteins associated with phagosomes, revealing conserved functional classes (vATPase subunits, GTPases, hydrolases, SNAREs, Rabs, cytoskeletal proteins).
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Assessing the utility of whole-genome amplified serum DNA for array-based high throughput genotyping.
PMID 20021669 · PMC2803178 · BMC genetics · 2009 · 8 claims · 8 setups
WGA DNA from archived serum samples produced low genotyping call rates and is unsuitable for high-resolution genotyping on SNP 6.0 arrays
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Has reproduction · 100
Complete human day 14 post-implantation embryo models from naive ES cells.
PMID 37673118 · PMC10584686 · Nature · 2023 · 8 claims · 8 setups
Genetically unmodified human naive ES cells can self-assemble into complete SEMs recapitulating nearly all post-implantation human embryo lineages (epiblast, hypoblast, extra-embryonic mesoderm, trophoblast).