Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 90
pysradb: A Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive.
PMID 31114675 · PMC6505635 · F1000Research · 2019 · 6 claims · 7 setups
pysradb provides a simple, user-friendly command-line interface for querying metadata and downloading datasets from SRA without requiring knowledge of a programming language.
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Has reproduction
All of gene expression (AOE): An integrated index for public gene expression databases.
PMID 31978081 · PMC6980531 · PloS one · 2020 · 8 claims · 5 setups
AOE integrates publicly available gene expression data from GEO, ArrayExpress, and GEA into a single searchable index.
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Full-text index only
A metadata approach for clinical data management in translational genomics studies in breast cancer.
PMID 19948017 · PMC3225860 · BMC medical genomics · 2009 · 8 claims · 5 setups
A metadata/CDE-based approach using CancerGrid's semantic web tools enables automatic integration of heterogeneous clinical datasets without loss of original detail
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Has reproduction · 64
GeMI: interactive interface for transformer-based Genomic Metadata Integration.
PMID 35657113 · PMC9216561 · Database : the journal of biological databases and curation · 2022 · 8 claims · 5 setups
GeMI is a web tool that uses a fine-tuned GPT2 model to extract 15 structured key-value attributes from free-text GEO sample metadata.
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Has reproduction · 100
poreCov-An Easy to Use, Fast, and Robust Workflow for SARS-CoV-2 Genome Reconstruction via Nanopore Sequencing.
PMID 34394197 · PMC8355734 · Frontiers in genetics · 2021 · 8 claims · 8 setups
poreCov is an easy-to-use, fast, and robust Nextflow-based workflow for reference-based SARS-CoV-2 genome reconstruction and lineage determination from nanopore sequencing data
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Has reproduction · 99
The systematic assessment of completeness of public metadata accompanying omics studies in the Gene Expression Omnibus data repository.
PMID 40926267 · PMC12421755 · Genome biology · 2025 · 8 claims · 3 setups
Over 25% of critical metadata are omitted, with only 74.8% of relevant phenotypes available in publications or public repositories.
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Has reproduction · 50
Workflow sharing with automated metadata validation and test execution to improve the reusability of published workflows.
PMID 36810800 · PMC9944229 · GigaScience · 2022 · 8 claims · 5 setups
Yevis is a system that builds a workflow registry which automatically validates and tests workflows prior to publication, ensuring they are 'reusable with confidence'.
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Has reproduction · 75
An informatics research platform to make public gene expression time-course datasets reusable for more scientific discoveries.
PMID 33247935 · PMC7698665 · Database : the journal of biological databases and curation · 2020 · 8 claims · 6 setups
GETc enables discovery and visualization of time-course gene expression data and analytical results from GEO
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Has reproduction · 80
Curation of over 10 000 transcriptomic studies to enable data reuse.
PMID 33599246 · PMC7904053 · Database : the journal of biological databases and curation · 2021 · 8 claims · 6 setups
Gemma is a curated database and bioinformatics system that addresses metadata, probe annotation, and expression data inconsistencies in GEO to enable transcriptomic data reuse
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Has reproduction · 78
Fungal metabarcoding data integration framework for the MycoDiversity DataBase (MDDB).
PMID 32463383 · PMC7734503 · Journal of integrative bioinformatics · 2020 · 6 claims · 5 setups
The MycoDiversity DataBase (MDDB) is a curated repository integrating public fungal metabarcoding data of environmental samples to study fungal biodiversity patterns in space and time.
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Has reproduction · 99
getSequenceInfo: a suite of tools allowing to get genome sequence information from public repositories.
PMID 35804320 · PMC9264741 · BMC bioinformatics · 2022 · 8 claims · 8 setups
getSequenceInfo (gSeqI) allows programmatic (CLI) or GUI-based retrieval of sequence data and metadata from GenBank, RefSeq, and ENA across Linux, MacOS, and Windows.
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Has reproduction · 100
Shiny-Calorie: a context-aware application for indirect calorimetry data analysis and visualization using R.
PMID 41640623 · PMC12867577 · Bioinformatics advances · 2026 · 8 claims · 8 setups
Shiny-Calorie is an open-source interactive application for transparent data and metadata integration, statistical analysis, and visualization of indirect calorimetry datasets.
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Full-text index only
The Genomes On Line Database (GOLD) in 2009: status of genomic and metagenomic projects and their associated metadata.
PMID 19914934 · PMC2808860 · Nucleic acids research · 2010 · 8 claims · 5 setups
GOLD is a comprehensive, centralized resource for tracking genome and metagenome sequencing projects and their associated metadata worldwide.
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Has reproduction · 95
The archives are half-empty: an assessment of the availability of microbial community sequencing data.
PMID 32859925 · PMC7455719 · Communications biology · 2020 · 8 claims · 5 setups
More than half of surveyed amplicon sequencing studies were affected by lack of data deposition, improper file formatting, or inconsistent labeling that impede reuse.
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Has reproduction · 83
Current status of use of high throughput nucleotide sequencing in rheumatology.
PMID 33408124 · PMC7789458 · RMD open · 2021 · 8 claims · 4 setups
RNA-Seq is the most represented HTS assay in rheumatology research (n=457, 65%), used for biomarker identification in blood or synovial tissue
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Has reproduction · 94
Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials.
PMID 33558569 · PMC7870661 · Scientific data · 2021 · 7 claims · 7 setups
A unified collection of 101 manually curated and homogenized transcriptomics datasets covering human, mouse, and rat ENM exposures in vitro and in vivo was compiled.
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Has reproduction · 88
Human methylome variation across Infinium 450K data on the Gene Expression Omnibus.
PMID 33937763 · PMC8061458 · NAR genomics and bioinformatics · 2021 · 8 claims · 6 setups
Approximately two-thirds of compiled HM450K samples are from blood, one-quarter from brain, and roughly one-third from cancer patients.
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Has reproduction · 57
KARAJ: An Efficient Adaptive Multi-Processor Tool to Streamline Genomic and Transcriptomic Sequence Data Acquisition.
PMID 36430895 · PMC9694301 · International journal of molecular sciences · 2022 · 8 claims · 6 setups
KARAJ automates end-to-end querying and downloading of genomic/transcriptomic sequence data from a list of PMCIDs, URLs, or accession numbers
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Has reproduction · 80
MCPmed: a call for Model Context Protocol-enabled bioinformatics web services for LLM-driven discovery.
PMID 41729821 · PMC12927880 · Briefings in bioinformatics · 2026 · 6 claims · 3 setups
Adapting MCP to bioinformatics web server backends provides a standardized, machine-actionable semantic layer linking API endpoints to scientific concepts and metadata.
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Has reproduction · 38
Genomic capacities for Reactive Oxygen Species metabolism across marine phytoplankton.
PMID 37098087 · PMC10128935 · PloS one · 2023 · 8 claims · 3 setups
Genes encoding superoxide (O2•−) scavenging are ubiquitous across phytoplankton, but their fractional gene allocation decreases with increasing cell radius, consistent with a nearly fixed core gene set.