Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Functional copy-number alterations in cancer.
PMID 18784837 · PMC2527508 · PloS one · 2008 · 8 claims · 3 setups
RAE is a comprehensive computational framework that robustly maps chromosomal alterations in tumor samples and statistically assesses their functional importance in cancer.
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The Proteomics Identifications database: 2010 update.
PMID 19906717 · PMC2808904 · Nucleic acids research · 2010 · 8 claims · 6 setups
PRIDE has become one of the main repositories for MS-based proteomics data, with substantial growth in data holdings over the last two years.
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Has reproduction · 71
Sustainable data analysis with Snakemake.
PMID 34035898 · PMC8114187 · F1000Research · 2021 · 8 claims · 4 setups
Reproducibility alone is insufficient for sustainable data analysis; transparency and adaptability are equally important additional properties.
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Has reproduction
Using prototyping to choose a bioinformatics workflow management system.
PMID 33630841 · PMC7906312 · PLoS computational biology · 2021 · 8 claims · 6 setups
Prototyping a subset of a project's actual workflow in candidate software offers a low-cost (time and effort) way to make a more informed software selection than relying solely on reviews and recommendations.
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Has reproduction · 96
Calibration-free NGS quantitation of mutations below 0.01% VAF.
PMID 34675197 · PMC8531361 · Nature communications · 2021 · 8 claims · 6 setups
QBDA (Quantitative Blocker Displacement Amplification) integrates UMI molecular barcoding with BDA variant enrichment to enable calibration-free VAF quantitation
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Animal models of gene-nutrient interactions.
PMID 19037208 · PMC2703433 · Obesity (Silver Spring, Md.) · 2008 · 8 claims · 5 setups
Mice and rats are well-suited models for human food selection because they share food preferences with humans and are supported by extensive genetic tools (sequenced genome, inbred strains, gene targeting, Cre-lox).