Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 67
Leveraging RNA-seq deconvolution to improve complex in vitro model characterization.
PMID 40701251 · PMC12391696 · The Journal of biological chemistry · 2025 · 8 claims · 6 setups
RNA-seq deconvolution can predict cell type proportions from bulk RNA-seq using scRNA-seq references, offering a useful characterization tool for CIVMs where single-cell methods are impractical
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Single-cell immunophenotyping identifies CD8+GZMK+IFNG+ T cells as a key immune population in cutaneous Lyme disease.
PMID 41729083 · PMC12956012 · JCI insight · 2026 · 8 claims · 7 setups
A clonally expanded CD8+GZMK+IFNG+ T cell population (subdivided into IFNGhi and IFNGint groups) is enriched in the EM lesion and shows an inflammatory, tissue-resident phenotype (GZMBlo/PRF1-) resembling tissue-enriched GZMK+ TteK cells
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Has reproduction · 94
A single-cell survey of Drosophila blood.
PMID 32396065 · PMC7237219 · eLife · 2020 · 8 claims · 6 setups
scRNA-seq of Drosophila larval hemocytes across unwounded, wounded, and wasp-infested conditions resolves 17 clusters spanning plasmatocytes, crystal cells, lamellocytes, and a non-hemocyte population.
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Has reproduction · 100
Intratumoral heterogeneity in microsatellite instability status at single-cell resolution.
PMID 41767255 · PMC12936829 · iScience · 2026 · 8 claims · 7 setups
A novel computational (Snakemake) pipeline quantifies intratumoral heterogeneity in MSI status at single-cell resolution
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Protocol to perform cell-type-specific transcriptome-wide association study using scPrediXcan framework.
PMID 41689808 · PMC12925207 · STAR protocols · 2026 · 6 claims · 6 setups
scPrediXcan enables cell-type-specific transcriptome-wide association studies (TWAS) by integrating deep learning-based prediction of gene expression from DNA sequence and epigenetic features.
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Has reproduction · 71
Cell type- and species-specific regulation of hepatic lncRNAs by TCDD-activated aryl hydrocarbon receptor.
PMID 41136526 · PMC12552753 · Scientific reports · 2025 · 8 claims · 6 setups
AHR-mediated lncRNA dysregulation may be a contributing mechanism in TCDD-elicited progression of steatosis to steatohepatitis with fibrosis