Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Processing and population genetic analysis of multigenic datasets with ProSeq3 software.
PMID 19797407 · PMC2778335 · Bioinformatics (Oxford, England) · 2009 · 8 claims · 7 setups
ProSeq3 is a program with a graphic user interface that simplifies preparation and basic population genetic analysis of multigenic DNA polymorphism datasets
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Grammar-based distance in progressive multiple sequence alignment.
PMID 18616828 · PMC2478692 · BMC bioinformatics · 2008 · 7 claims · 3 setups
A grammar-based (LZ complexity) distance metric can be used to determine the order in which sequences are progressively pairwise aligned
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Has reproduction · 59
WASP: a versatile, web-accessible single cell RNA-Seq processing platform.
PMID 33736596 · PMC7977290 · BMC genomics · 2021 · 7 claims · 7 setups
WASP is a software platform for processing Drop-Seq-based scRNA-seq data generated with ddSEQ or 10x protocols, combining a Snakemake pre-processing pipeline with an R Shiny post-processing application.
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Has reproduction · 86
The selection of software and database for metagenomics sequence analysis impacts the outcome of microbial profiling and pathogen detection.
PMID 37027361 · PMC10081788 · PloS one · 2023 · 7 claims · 7 setups
Obtaining an accurate species-level microbial profile using current direct-read metagenomics profiling software is still a challenging task.
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Has reproduction
Using prototyping to choose a bioinformatics workflow management system.
PMID 33630841 · PMC7906312 · PLoS computational biology · 2021 · 8 claims · 6 setups
Prototyping a subset of a project's actual workflow in candidate software offers a low-cost (time and effort) way to make a more informed software selection than relying solely on reviews and recommendations.
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Serum diagnosis of diffuse large B-cell lymphomas and further identification of response to therapy using SELDI-TOF-MS and tree analysis patterning.
PMID 18163913 · PMC2242801 · BMC cancer · 2007 · 8 claims · 8 setups
SELDI-TOF-MS serum proteomic patterns analyzed by decision tree classification (Biomarker Pattern Software) can discriminate DLBCL patients from healthy controls with high sensitivity and specificity.
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Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival.
PMID 18778477 · PMC2553089 · BMC medicine · 2008 · 7 claims · 7 setups
A custom BOAC SNP panel of 3404 SNPs in 983 genes was developed using the Affymetrix GeneChip Targeted Genotyping Platform, focused on non-synonymous coding SNPs and regulatory-region SNPs in candidate genes.
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PRIDE: a public repository of protein and peptide identifications for the proteomics community.
PMID 16381953 · PMC1347500 · Nucleic acids research · 2006 · 8 claims · 6 setups
PRIDE is a PSI-compliant public repository for protein and peptide identifications, associated post-translational modifications, and supporting mass spectra from the scientific literature.
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Has reproduction · 93
aCLImatise: automated generation of tool definitions for bioinformatics workflows.
PMID 33325479 · PMC8016486 · Bioinformatics (Oxford, England) · 2021 · 6 claims · 3 setups
aCLImatise automatically generates workflow-language tool definitions by parsing a command-line tool's help output
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Has reproduction · 71
Hyb: a bioinformatics pipeline for the analysis of CLASH (crosslinking, ligation and sequencing of hybrids) data.
PMID 24211736 · PMC3969109 · Methods (San Diego, Calif.) · 2014 · 8 claims · 6 setups
The 'hyb' pipeline detects, calls, folds and annotates chimeric reads from CLASH high-throughput sequencing data.