Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• In vivo dual RNA-Seq uncovers key effectors of epithelial barrier disruption by an extracellular pathogen.

  PMID 41634022 · PMC12966279 · Nature communications · 2026 · 8 claims · 8 setups

  Full-text index only

  Dual RNA-Seq of L. interrogans-infected hamsters reveals the in vivo host-pathogen transcriptomic landscape during infection

  golden interrogans hamster epithelial dual rna-seq qpcr

• 4-Methylcytosine DNA modification is critical for global epigenetic regulation and virulence in the human pathogen Leptospira interrogans.

  PMID 33301041 · PMC7708080 · Nucleic acids research · 2020 · 7 claims · 8 setups

  Has reproduction · 78

  Inactivation of the orphan 4mC methyltransferase (LomA) causes complete abrogation of CTAG motif methylation genome-wide

  interrogans mdck-1 syrian smrt rna-seq rt-qpcr

• COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.

  PMID 35870428 · PMC9297827 · EBioMedicine · 2022 · 8 claims · 8 setups

  Has reproduction · 85

  COVID-19 lung disease resembles IPF at a fundamental level, recapitulating ViP/IPF gene expression patterns, an IL15-centric cytokine storm, and AT2 cytopathic changes (injury, DNA damage, transient progenitor-state arrest, senescence/SASP).

  lung covid-19 interaction pre-clinical composite single-cell kaplan-meier