Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: expression ✕ Assay: rnp ✕ Clear

JunB Is Critical for Survival of T Helper Cells.

PMID 35837408 · PMC9273772 · Frontiers in immunology · 2022 · 7 claims · 7 setups

Has reproduction · 69

JunB is required for clonal expansion of Th1, Th2, and Th17 cells

ot-ii junb naive th1 flow adoptive th1
Integrative miRNA-mRNA Network and Molecular Dynamics-Based Identification of Therapeutic Candidates for Paroxysmal Nocturnal Hemoglobinuria.

PMID 41599741 · PMC12845513 · Pharmaceuticals (Basel, Switzerland) · 2026 · 8 claims · 8 setups

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A PIGA-knockout (PIGA-KO) THP-1 cell model was successfully established using CRISPR/Cas9 RNP technology as a PNH model

thp-1 literature-validated pnh cxcl8 crispr rt-qpcr bulk
Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation.

PMID 41674383 · PMC12895067 · Nucleic acids research · 2026 · 7 claims · 8 setups

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HNRNPU forms extensive protein networks including an association with the mammalian SWI/SNF chromatin-remodeling complex

ipsc-derived computational neocortical ip-ms formaldehyde alphapulldown expression-weighted
Characterization of Phytoene Desaturase Knockout Carotenoid-Deficient Microalgal Mutants Generated by Cas9-Ribonucleoprotein Complexes.

PMID 41757451 · PMC12947057 · Physiologia plantarum · 2026 · 8 claims · 8 setups

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Cas9-ribonucleoprotein (RNP) complexes with dual sgRNAs targeting PDS exon 1 and a donor DNA sequence successfully generated multiple white PDS-knockout Chlamydomonas transformants

pcr-amplified chlamydomonas transformant methanol rnp electroporation-based pcr
Omics-aided design genome editing strategy for challenging human immortalized cell models.

PMID 41678468 · PMC12900285 · PloS one · 2026 · 6 claims · 4 setups

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Omics profiling identifies bottlenecks associated with poor precise KI efficiency in hard-to-engineer cells

mcf7 deep-targeted bulk dia-based
Vitamin C Conditioning Generates Tumor-Targeting CAR T Cells with Superior Cytotoxicity and Fitness in a Posttransplant Lymphoproliferative Disorder Tumor Model.

PMID 41416402 · PMC13136873 · Molecular cancer therapeutics · 2026 · 8 claims · 8 setups

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VitC conditioning enhances transduction efficiency and proliferative capacity, yielding a higher yield of CD4+ and CD8+ CAR19-Ts

cd3+ je6-1 car19-ts coculture flow nf-κb cytotoxicity

Experiments

JunB Is Critical for Survival of T Helper Cells.

Integrative miRNA-mRNA Network and Molecular Dynamics-Based Identification of Therapeutic Candidates for Paroxysmal Nocturnal Hemoglobinuria.

Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation.

Characterization of Phytoene Desaturase Knockout Carotenoid-Deficient Microalgal Mutants Generated by Cas9-Ribonucleoprotein Complexes.

Omics-aided design genome editing strategy for challenging human immortalized cell models.

Vitamin C Conditioning Generates Tumor-Targeting CAR T Cells with Superior Cytotoxicity and Fitness in a Posttransplant Lymphoproliferative Disorder Tumor Model.