Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Shooting darts: co-evolution and counter-adaptation in hermaphroditic snails.

  PMID 15799778 · PMC1080126 · BMC evolutionary biology · 2005 · 8 claims · 6 setups

  Full-text index only

  Dart shooting introduces an allohormone that inhibits digestion of donated sperm, increasing the amount reaching the spermathecae and fertilizing eggs, thereby manipulating the mating partner's sperm storage.

  dart-possessing same land cantareus 28s shimodaira-hasegawa principal

• Machine learning reveals microbial interactions driving plastic degradation across plastisphere environments.

  PMID 41657981 · PMC12876002 · Frontiers in microbiology · 2025 · 6 claims · 7 setups

  Has reproduction · 87

  Wastewater plastispheres harbor the most diverse and compositionally even microbial communities among the three habitats.

  ocean wastewater surface plastisphere 16s alpha beta

• Electroacupuncture reshapes the microbial co-occurrence networks related to the behavioral and psychological symptoms of dementia in Alzheimer's disease.

  PMID 41676443 · PMC12806058 · iMetaOmics · 2025 · 8 claims · 5 setups

  Has reproduction · 77

  Microbial keystone species and gut microbiota composition are highly variable during pathological development of BPSD in AD

  appswe app gut 16s random open

• Sequencing of 16S rRNA gene: a rapid tool for identification of Bacillus anthracis.

  PMID 12396926 · PMC2730316 · Emerging infectious diseases · 2002 · 7 claims · 4 setups

  Full-text index only

  All 86 B. anthracis isolates tested share an identical 16S rRNA gene sequence, designated 16S type 6

  bacillus clinical additional 16s nested comparative

• Environment and Co-occurring Native Mussel Species, but Not Host Genetics, Impact the Microbiome of a Freshwater Invasive Species (Corbicula fluminea).

  PMID 35444631 · PMC9014210 · Frontiers in microbiology · 2022 · 7 claims · 7 setups

  Has reproduction · 55

  The gut microbiome of C. fluminea is diverse, differs with environmental conditions, and varies spatially among rivers, but is unrelated to host genetic variation

  corbicula six sediment filtered 16s radseq picrust2

• Metatranscriptomics of the human oral microbiome during health and disease.

  PMID 24692635 · PMC3977359 · mBio · 2014 · 8 claims · 8 setups

  Has reproduction · 62

  Disease-associated periodontal communities display conserved community-level metabolic gene expression profiles between patients, whereas the metabolic gene expression of individual species is highly variable between patients.

  patient-matched subset health rna-seq rrna comparison metatranscriptomics

• Helminth genomics: The implications for human health.

  PMID 19855829 · PMC2757907 · PLoS neglected tropical diseases · 2009 · 8 claims · 7 setups

  Full-text index only

  More than two billion people (one-third of humanity) are infected with helminth parasites, causing major morbidity, mortality, and poverty maintenance

  helminth nematode schistosoma strongyloides phylogenetic genome expressed

• The effect of 16S rRNA region choice on bacterial community metabarcoding results.

  PMID 30720800 · PMC6362892 · Scientific data · 2019 · 8 claims · 6 setups

  Has reproduction · 59

  The V2-V3 16S rRNA fragment has higher resolution for lower-rank taxa (genera and species) than V3-V4, allowing more precise distance-based clustering of reads into species-level OTUs.

  lake pcr miseq species-rank 16s extraction pcr

• RiboTaxa: combined approaches for rRNA genes taxonomic resolution down to the species level from metagenomics data revealing novelties.

  PMID 36159175 · PMC9492272 · NAR genomics and bioinformatics · 2022 · 8 claims · 6 setups

  Has reproduction · 66

  RiboTaxa, combining BBTools, FastQC, SortMeRNA, MetaRib, EMIRGE, VSEARCH, BBMap and QIIME 2's Sklearn classifier, was built as a pipeline for SSU rRNA-based taxonomic profiling of metagenomics data.

  microbial reconstructed synthetic real shotgun ssu full-length

• Microbial Community Shifts Associated With the Ongoing Stony Coral Tissue Loss Disease Outbreak on the Florida Reef Tract.

  PMID 31608047 · PMC6769089 · Frontiers in microbiology · 2019 · 7 claims · 5 setups

  Has reproduction · 93

  Five amplicon sequence variants (unclassified Flavobacteriales, Fusibacter, Planktotalea, Algicola, and Vibrio) were consistently enriched in disease lesions across three coral species (M. cavernosa, D. labyrinthiformis, D. stokesii)

  coral cavernosa 16s differential principal

• Different Intestinal Microbiota with Growth Stages of Three-Breed Hybrid Pig.

  PMID 35978648 · PMC9377885 · BioMed research international · 2022 · 7 claims · 5 setups

  Has reproduction · 75

  The composition and relative abundance of intestinal microbiota in three-breed hybrid pigs differ significantly across growth stages (60, 120, 180 days)

  fecal same 16s otu alpha

• Diversity and Structure of the Prokaryotic Community in Tropical Monomictic Reservoir.

  PMID 40072582 · PMC11903632 · Microbial ecology · 2025 · 7 claims · 6 setups

  Has reproduction

  Diversity and structure of the prokaryotic community exhibit spatio-temporal variations driven by the annual circulation-stratification hydrodynamic cycle.

  water 16s vertical 16s sequence water

• GAL08, an Uncultivated Group of Acidobacteria, Is a Dominant Bacterial Clade in a Neutral Hot Spring.

  PMID 35087491 · PMC8787282 · Frontiers in microbiology · 2021 · 8 claims · 8 setups

  Has reproduction · 50

  GAL08 is a dominant bacterial clade in a neutral hot spring, comprising up to 29.2% of the community by relative read abundance and up to 4.7 × 10^5 16S rRNA gene copies per gram sediment.

  dewar dchs_gal08 hoodoo gal08 16s qpcr single

• Metagenomic study of the oral microbiota by Illumina high-throughput sequencing.

  PMID 19796657 · PMC3568755 · Journal of microbiological methods · 2009 · 8 claims · 6 setups

  Full-text index only

  The 16S rRNA V5 hypervariable region, amplified as a short ~82-base segment, provides reliable taxonomic identification of oral bacteria against public databases like HOMD.

  pooled 16s sequenced topo 16s primer taxonomic

• Elevated phenylacetylglutamine caused by gut dysbiosis associated with type 2 diabetes increases neutrophil extracellular traps formation and exacerbates brain infarction.

  PMID 40471587 · PMC12599254 · Clinical science (London, England : 1979) · 2025 · 7 claims · 8 setups

  Full-text index only

  Plasma PAGln levels are significantly higher in ischemic stroke patients with T2D than in those without T2D

  fecal plasma sprague-dawley cerebral 16s metagenome targeted

• eDNAmap: A Metabarcoding Web Tool for Comparing Marine Biodiversity, With Special Reference to Teleost Fish.

  PMID 41189540 · PMC12627913 · Molecular ecology resources · 2026 · 6 claims · 5 setups

  Has reproduction · 59

  eDNAmap is a web-based platform that stores marine eDNA metabarcoding data and lets users plot sampling locations, generate heatmaps, and run nMDS/cluster analyses on uploaded or database species/ASV composition data.

  teleost dinoflagellates 12s asv edna blast phylogenetic

• Comparative Genomics Provides Insight into the Function of Broad-Host Range Sponge Symbionts.

  PMID 34519538 · PMC8546597 · mBio · 2021 · 8 claims · 8 setups

  Has reproduction · 90

  Eleven new genomes were added to the Tethybacterales order and a novel family (Polydorabacteraceae) was identified

  tsitsikamma tethybacterales putative bin genome 16s multi-locus

• Bioavailable Nutrients (N and P) and Precipitation Patterns Drive Cyanobacterial Blooms in Missisquoi Bay, Lake Champlain.

  PMID 34683418 · PMC8537112 · Microorganisms · 2021 · 8 claims · 8 setups

  Has reproduction · 67

  High concentrations of N and P were typically measured in April and May, before blooms occurred.

  water filtered lugol's-iodine-preserved 16s 16s nutrient situ

• Analysis of the Taxonomy, Synteny, and Virulence Factors for Soft Rot Pathogen Pectobacterium aroidearum in Amorphophallus konjac Using Comparative Genomics.

  PMID 35910650 · PMC9326479 · Frontiers in microbiology · 2022 · 8 claims · 8 setups

  Has reproduction · 100

  The causal agent of konjac soft rot in China is Pectobacterium aroidearum, confirmed via in vitro/in vivo pathogenicity tests, ANI, dDDH, and phylogenomic analysis.

  amorphophallus 6-month-old bacterial aroidearum pathogenicity pectinolytic 16s

• Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements.

  PMID 36253367 · PMC9576764 · Nature communications · 2022 · 8 claims · 4 setups

  Has reproduction · 100

  The P. magna mitoribosome contains rRNA split into 13 fragments (LSU1-8, SSU1-4, mt-5S)

  mitoribosome polytomella cross-species single-particle novo comparative