Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Recurring mutations found by sequencing an acute myeloid leukemia genome.

  PMID 19657110 · PMC3201812 · The New England journal of medicine · 2009 · 8 claims · 8 setups

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  Deep paired tumor/normal whole-genome sequencing of a cytogenetically normal AML-M1 genome identified 12 somatic coding (tier 1) mutations and 52 somatic tier 2 (conserved/regulatory) mutations.

  aml-m1 tumor bone additional whole-genome snp gene-expression

• Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer.

  PMID 39018396 · PMC466953 · Science advances · 2024 · 8 claims · 8 setups

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  Primate-specific ERVs are a rich source of enhancers displaying cancer-specific activity across multiple tumor types

  cancer hct116 tcga colorectal atac-seq chip-seq bulk

• Deciphering the RNA landscapes on mammalian cell surfaces.

  PMID 40973153 · PMC12959771 · Protein & cell · 2026 · 7 claims · 8 setups

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  AMOUR, a T7 RNA polymerase-based in-situ linear amplification method, enables high-throughput profiling of outer membrane surface RNAs while preserving plasma membrane integrity, including in rare primary cell populations.

  live hucb-mncs hela amour-treated transmission-through-dye intact-surface-fish amour

• First genome assemblies of Neotropical Thoracobombus bumblebees Bombus pauloensis and Bombus pullatus.

  PMID 41436027 · PMC12958814 · G3 (Bethesda, Md.) · 2026 · 7 claims · 8 setups

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  This study produced the first genome assemblies of Neotropical Bombus (Thoracobombus) species, B. pauloensis and B. pullatus

  pauloensis masked long-read k-mer novo

• Epimutations driven by RNAi or heterochromatin evoke transient antimicrobial drug resistance in pathogenic Mucor fungi.

  PMID 41628159 · PMC12863538 · PLoS biology · 2026 · 8 claims · 8 setups

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  In M. bainieri, most (90%) FK506-resistant isolates are unstable/transient and revert to drug sensitivity without any detectable DNA mutation

  mucor fk506-resistant bainieri drug sanger serial

• Human CRAMP1 specifically promotes the expression of histone H1 genes.

  PMID 41663757 · PMC12979687 · EMBO reports · 2026 · 8 claims · 8 setups

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  CRAMP1 is a selective regulator of histone H1 gene expression that does not significantly affect core histone gene expression

  cancer hek293t rpe1 genome-wide immunoprecipitation-mass western

• The genome sequence of Menetries' Clouded Yellow, Colias thisoa Ménétriès, 1832 (Lepidoptera: Pieridae).

  PMID 41716938 · PMC12914173 · Wellcome open research · 2026 · 8 claims · 7 setups

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  A chromosome-level, haplotype-resolved genome assembly was generated for Colias thisoa as part of Project Psyche

  colias pacbio assembled scaffolded pacbio hi-c k-mer

• Single-cell analysis of signalling and transcriptional responses to type I interferons.

  PMID 41896367 · PMC13172048 · EMBO reports · 2026 · 7 claims · 6 setups

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  Different immune cell types show cell-type-specific patterns of STAT phosphorylation and gene expression changes in response to type I IFN

  freshly pbmcs mass rt-qpcr bulk

• PeakPrime: a peak-guided primer design pipeline for target enrichment in 3'-end RNA-seq.

  PMID 41919010 · PMC13034549 · Bioinformatics advances · 2026 · 8 claims · 7 setups

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  PeakPrime is a reproducible Nextflow pipeline that calls 3′ RNA-seq coverage peaks (MACS2), selects exonic windows, designs strand-appropriate primers (Primer3), and screens specificity (Bowtie2)

  imr-32 universal candidate 10m-read rna-seq targeted quantitative

• Mouse placentae generated by in vitro fertilization exhibit altered gene expression, activated hypoxia responses, and reduced fitness†.

  PMID 40874534 · PMC12808545 · Biology of reproduction · 2026 · 6 claims · 6 setups

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  IVF-conceived mouse placentae exhibit global and cell type–specific gene expression differences compared to FB placentae

  e12.5 differentially trophoblast placenta single-nucleus pseudobulk pathway

• Systems biology of gene regulation fulfills its promise.

  PMID 16719937 · PMC1779525 · Genome biology · 2006 · 8 claims · 8 setups

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  Suz12, a Polycomb Group complex component, has DNA targets identifiable by ChIP-chip and can silence large genomic regions in a cell-type-specific manner.

  unspecified embryonic five yeast chip-chip chip-pet computational

• Shaken not stirred: a global research cocktail served in Hinxton.

  PMID 18036269 · PMC2258181 · Genome biology · 2007 · 8 claims · 8 setups

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  Network-guided reverse genetics using probabilistic functional gene networks (e.g. YeastNet, WormNet) reduces the search space for identifying genes in a given biological process

  budding caenorhabditis drosophila escherichia two-color double chip-chip

• ENCODE whole-genome data in the UCSC Genome Browser.

  PMID 19920125 · PMC2808953 · Nucleic acids research · 2010 · 7 claims · 8 setups

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  The UCSC ENCODE Data Coordination Center serves as the primary repository for ENCODE experimental results, providing access via Genome Browser, Table Browser, and FTP download.

  lines chip-seq dnase-seq rna-seq