Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 1.1k

System / cell line: patients ✕ Clear

Comparative single-cell landscape of immune cells in human livers affected HBV and non-viral cirrhosis.

PMID 41815278 · PMC12971635 · Frontiers in medicine · 2025 · 8 claims · 7 setups

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Macrophage-PLCG2 (anti-inflammatory) and CD8+ T-FABP5 subsets are expanded in HBV cirrhosis compared to non-viral cirrhosis

liver myeloid scrna-seq spatial pathway
CCL3+ Neutrophil Signature Predicts Response to Neoadjuvant Toripalimab plus Chemotherapy in Patients with Hypopharyngeal Squamous Cell Carcinoma: A Phase II Trial.

PMID 41817286 · PMC13223550 · Clinical cancer research : an official journal of the American Association for Cancer Research · 2026 · 7 claims · 8 setups

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A proinflammatory, CCL3-high neutrophil subset (Neu_CCL3) is significantly enriched in the pretreatment tumor microenvironment of patients who respond to nCIT.

pretreatment microarray cohorts moc1 single-cell bulk immunohistochemistry
Mutation and deletion analysis of GFR alpha-1, encoding the co-receptor for the GDNF/RET complex, in human brain tumours.

PMID 10408842 · PMC2362327 · British journal of cancer · 1999 · 8 claims · 3 setups

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No mutations were found in the coding region of GDNF in any of the 36 brain tumours analysed

sporadic tumour tumour-derived pcr loss semi-quantitative
Correlation of mutation and immunohistochemistry of p53 in hepatocellular carcinomas in Korean people.

PMID 12483005 · PMC3054961 · Journal of Korean medical science · 2002 · 6 claims · 3 setups

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5% immunoreactive tumor cells is a reliable IHC threshold to detect p53 mutations in HCC

hcc genomic pcr immunohistochemistry pcr-sscp sequencing
Development of proteomic patterns for detecting lung cancer.

PMID 14757945 · PMC3851077 · Disease markers · 2003 · 8 claims · 3 setups

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A decision tree classification algorithm built on three serum protein mass peaks (8122Da, 1452Da, 1610Da) can discriminate lung cancer patients from healthy controls

serum pooled seldi-tof-ms decision reproducibility
Detection of an Ala601Thr mutation of plasminogen gene in 3 out of 36 Korean patients with deep vein thrombosis.

PMID 12692411 · PMC3055032 · Journal of Korean medical science · 2003 · 7 claims · 3 setups

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Dysplasminogenemia was identified in 3 of 36 (8.3%) unrelated Korean DVT patients.

plasma genomic amidolytic immunoturbidimetric pcr
Analysis of polymorphic TGFB1 codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults.

PMID 15212689 · PMC441379 · BMC medical genetics · 2004 · 8 claims · 3 setups

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Arg25Pro heterozygous genotype is significantly less frequent in CLP patients (3.3%) than in healthy controls (16.7%)

peripheral genomic platelet-poor real-time sanger enzyme-linked
Increased risk of breast cancer among female relatives of patients with ataxia-telangiectasia: a causal relationship?

PMID 16222317 · PMC2361617 · British journal of cancer · 2005 · 6 claims · 3 setups

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Breast cancer risk is strongly and significantly elevated specifically among mothers of AT patients (SIR=7.14), consistent with Olsen et al's finding (SIR=6.7)

blood same retrospective atm weighted
Mutational analysis of the PITX2 coding region revealed no common cause for transposition of the great arteries (dTGA).

PMID 15890066 · PMC1142516 · BMC medical genetics · 2005 · 7 claims · 3 setups

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Screening of the PITX2 coding region and exon-intron junctions in 96 dTGA patients revealed no stop or frameshift mutations.

genomic pcr denaturing direct
EDAR mutation in autosomal dominant hypohidrotic ectodermal dysplasia in two Swedish families.

PMID 17125505 · PMC1684249 · BMC medical genetics · 2006 · 6 claims · 3 setups

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A nonsense mutation c.1072C>T (p.Arg358X) in exon 12 of EDAR was identified in affected individuals from both Swedish families and is disease-specific

genomic patients dhplc pcr clinical
Prevalence of H63D, S65C and C282Y hereditary hemochromatosis gene mutations in Slovenian population by an improved high-throughput genotyping assay.

PMID 18036208 · PMC2253505 · BMC medical genetics · 2007 · 7 claims · 3 setups

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Improved short, non-overlapping TaqMan MGB probes accurately and simultaneously discriminate the H63D, S65C and C282Y HFE polymorphisms without cross-interference between the closely spaced codon 63/65 SNPs.

genomic real-time rflp sequencing
Genetic association study and meta-analysis of the HTR2C Cys23Ser polymorphism and migraine.

PMID 17901921 · PMC3451673 · The journal of headache and pain · 2007 · 8 claims · 3 setups

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The HTR2C Cys23Ser polymorphism is not significantly associated with migraine or migraine with aura in the case-control study

blood-derived migraine pooled allelic case-control meta-analysis
Pilot proteomic profile of differentially regulated proteins in right atrial appendage before and after cardiac surgery using cardioplegia and cardiopulmonary bypass.

PMID 18824761 · PMC2629397 · Circulation · 2008 · 8 claims · 3 setups

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CP/CPB causes multiple consistent, reproducible changes in the human myocardial (right atrial) protein profile

right excised 2-dimensional tandem sds-page
Analysis of large deletions in BRCA1, BRCA2 and PALB2 genes in Finnish breast and ovarian cancer families.

PMID 18501021 · PMC2413256 · BMC cancer · 2008 · 8 claims · 3 setups

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A large genomic deletion spanning exons 1A-13 of BRCA1 (>43 kb, including the promoter) was identified in one Northern Finnish family with a history of ovarian cancer.

germline mlpa
Peeling off the layers: skin taping and a novel proteomics approach to study atopic dermatitis.

PMID 19748658 · PMC8648281 · The Journal of allergy and clinical immunology · 2009 · 8 claims · 3 setups

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Noninvasive D-Squame tape stripping coupled with MS proteomics can profile the AD skin proteome

skin extracted lesion skin lc-ms statistical
Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria.

PMID 19644383 · PMC2815152 · Journal of acquired immune deficiency syndromes (1999) · 2009 · 8 claims · 3 setups

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K65R mutation is present in a substantial proportion (10.9%) of Nigerian patients failing first-line ART, including many with no prior tenofovir exposure

plasma k65r-positive hiv-1 comparative clinical
The rate of the 6174delT founder Jewish mutation in BRCA2 in patients with non-colonic gastrointestinal tract tumours in Israel.

PMID 11207041 · PMC2363777 · British journal of cancer · 2001 · 8 claims · 2 setups

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The 6174delT BRCA2 mutation carrier rate is significantly higher in Jewish Ashkenazi non-colonic GI cancer patients (8.6%) than in the general Ashkenazi population (1.16%)

unselected peripheral extraction pcr
Application of serum SELDI proteomic patterns in diagnosis of lung cancer.

PMID 16029516 · PMC1183195 · BMC cancer · 2005 · 6 claims · 2 setups

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A five-protein-peak SELDI decision-tree pattern (11493, 6429, 8245, 5335, 2538 Da) distinguishes lung cancer sera from healthy control sera with relatively high sensitivity and specificity

serum seldi-tof-ms electrochemiluminescent
Proteomic alteration in gastic adenocarcinomas from Japanese patients.

PMID 17187689 · PMC1774573 · Molecular cancer · 2006 · 7 claims · 2 setups

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2D-EP and LC-ESI-MS/MS identified 69 different proteins in gastric tumor tissue, classifiable into cytoskeletal, stress/chaperone, glycolytic, metabolic, tumor suppressor, and stomach-specific categories.

paired two-dimensional rt-pcr
Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis.

PMID 17163998 · PMC1762011 · BMC gastroenterology · 2006 · 7 claims · 2 setups

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The ACE I/D polymorphism shows no significant association with TCP or FCPD pathogenesis, fibrosis, or progression

peripheral pcr sanger

Experiments

Comparative single-cell landscape of immune cells in human livers affected HBV and non-viral cirrhosis.

CCL3+ Neutrophil Signature Predicts Response to Neoadjuvant Toripalimab plus Chemotherapy in Patients with Hypopharyngeal Squamous Cell Carcinoma: A Phase II Trial.

Mutation and deletion analysis of GFR alpha-1, encoding the co-receptor for the GDNF/RET complex, in human brain tumours.

Correlation of mutation and immunohistochemistry of p53 in hepatocellular carcinomas in Korean people.

Development of proteomic patterns for detecting lung cancer.

Detection of an Ala601Thr mutation of plasminogen gene in 3 out of 36 Korean patients with deep vein thrombosis.

Analysis of polymorphic TGFB1 codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults.

Increased risk of breast cancer among female relatives of patients with ataxia-telangiectasia: a causal relationship?

Mutational analysis of the PITX2 coding region revealed no common cause for transposition of the great arteries (dTGA).

EDAR mutation in autosomal dominant hypohidrotic ectodermal dysplasia in two Swedish families.

Prevalence of H63D, S65C and C282Y hereditary hemochromatosis gene mutations in Slovenian population by an improved high-throughput genotyping assay.

Genetic association study and meta-analysis of the HTR2C Cys23Ser polymorphism and migraine.

Pilot proteomic profile of differentially regulated proteins in right atrial appendage before and after cardiac surgery using cardioplegia and cardiopulmonary bypass.

Analysis of large deletions in BRCA1, BRCA2 and PALB2 genes in Finnish breast and ovarian cancer families.

Peeling off the layers: skin taping and a novel proteomics approach to study atopic dermatitis.

Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria.

The rate of the 6174delT founder Jewish mutation in BRCA2 in patients with non-colonic gastrointestinal tract tumours in Israel.

Application of serum SELDI proteomic patterns in diagnosis of lung cancer.

Proteomic alteration in gastic adenocarcinomas from Japanese patients.

Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis.