Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Restoring immune homeostasis in atherosclerotic plaques via inorganic violet phosphorus nano-immunotherapy.

  PMID 41494534 · PMC12866099 · Cell reports. Medicine · 2026 · 8 claims · 8 setups

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  VPNS@P selectively accumulates in immune cells within atherosclerotic plaques (predominantly macrophages and monocytes, partly T and B cells) with minimal off-target uptake by non-immune vascular cells

  vpns@p cell-free raw264.7 bone-marrow-derived tem ros-scavenging cck-8

• scXDR: drug response prediction across single-cell datasets via heterogeneous network transfer learning.

  PMID 41507436 · PMC12859067 · Communications biology · 2026 · 7 claims · 7 setups

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  scXDR outperforms seven methods that transfer drug response information from bulk RNA-seq to single-cell data, across all four evaluated scenarios

  single-cell scrna-seq scxdr gse117872 heterogeneous benchmarking type

• Dictionary of human intestinal organoid responses to secreted niche factors at single cell resolution.

  PMID 41513700 · PMC12891662 · Nature communications · 2026 · 8 claims · 8 setups

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  Cytomix (TNFɑ+IFNɣ+IL1β) treatment of human colon organoids best recapitulates molecular features of human IBD compared to DSS or irradiation injury models.

  colon cytomix-treated scrna-seq immunofluorescence activated

• DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AID.

  PMID 41526379 · PMC12905297 · Nature communications · 2026 · 8 claims · 8 setups

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  DOT1L and super elongation complex (SEC) components are proximal to nuclear AID by BioID

  flp-in ch12f3 dot1l-deficient splenic bioid shrna rt-qpcr

• A rigorous method for multigenic families' functional annotation: the peptidyl arginine deiminase (PADs) proteins family example.

  PMID 16271148 · PMC1310624 · BMC genomics · 2005 · 8 claims · 5 setups

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  Integrating EST-based expression data with phylogenetic analysis is a valid new method for functionally annotating multigenic protein families

  pad phylogenetic est est-based

• Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation.

  PMID 19745699 · PMC2788075 · The American journal of surgical pathology · 2009 · 8 claims · 3 setups

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  Abnormal nuclear β-catenin labeling is common in SSAs but essentially absent in hyperplastic polyps (HPs)

  colorectal microdissected archival immunohistochemistry pcr histopathologic

• Macrel: antimicrobial peptide screening in genomes and metagenomes.

  PMID 33384902 · PMC7751412 · PeerJ · 2020 · 8 claims · 8 setups

  Has reproduction · 83

  Macrel introduces a novel set of 22 peptide features (6 local, 16 global), including a new Free Energy Transition (FET) feature group, for AMP and hemolytic activity classification

  curated hemopi-1 xiao peptide random benchmark homology-aware

• Accurate prediction of metagenome-assembled genome completeness by MAGISTA, a random forest model built on alignment-free intra-bin statistics.

  PMID 35248155 · PMC8898458 · Environmental microbiome · 2022 · 7 claims · 7 setups

  Has reproduction · 83

  MAGISTA, a random forest model built on alignment-free intra-bin distance-distribution statistics, can estimate MAG completeness and purity without relying on reference marker genes.

  pooled hc227 contig sets shotgun novo alignment-free

• DeeReCT-APA: Prediction of Alternative Polyadenylation Site Usage Through Deep Learning.

  PMID 33662629 · PMC9801043 · Genomics, proteomics & bioinformatics · 2022 · 8 claims · 8 setups

  Has reproduction · 50

  DeeReCT-APA quantitatively predicts the usage of all competing PASs of a gene simultaneously, rather than casting the problem as pairwise comparison like prior methods.

  fibroblast genomic same 3'-region 3'-mrna deep

• The UCSC genome browser database: update 2007.

  PMID 17142222 · PMC1669757 · Nucleic acids research · 2007 · 8 claims · 8 setups

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  The UCSC Genome Browser Database provides sequence and annotation data for 13 vertebrate and 19 invertebrate species as of September 2006.

  hg17 genome lines xenopus comparative snp linkage

• MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes.

  PMID 17090601 · PMC1781136 · Nucleic acids research · 2007 · 8 claims · 8 setups

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  MAPU is a unified, freely accessible database integrating organellar, cellular, tissue and body fluid proteomes generated by high-resolution mass spectrometry.

  urine tear seminal breast gel lc-ms3 in-depth

• NCBI Reference Sequences: current status, policy and new initiatives.

  PMID 18927115 · PMC2686572 · Nucleic acids research · 2009 · 7 claims · 5 setups

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  RefSeq is a curated, non-redundant, explicitly linked database of nucleotide and protein sequences spanning genomes, transcripts and proteins across prokaryotes, eukaryotes and viruses

  microbial bacterial prokaryotic refseq spliced structural functional

• The genome sequence of the soldier beetle, Malthodes minimus (Linnaeus, 1758) (Coleoptera: Cantharidae).

  PMID 41769330 · PMC12949377 · Wellcome open research · 2026 · 8 claims · 8 setups

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  The Malthodes minimus genome assembly has a total length of 583.60 Mb, with 97.75% scaffolded into 7 chromosomal pseudomolecules including X and Y sex chromosomes

  malthodes pacbio assembled alternate pacbio hi-c barcoding

• The genome sequence of the Spanish Fritillary, Euphydryas desfontainii (Godart, 1819) (Lepidoptera: Nymphalidae).

  PMID 41835093 · PMC12988360 · Wellcome open research · 2026 · 7 claims · 8 setups

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  A chromosome-level genome assembly was produced for Euphydryas desfontainii from a single male specimen, comprising two haplotypes of 755.68 Mb and 751.57 Mb

  organism euphydryas pacbio hi-c k-mer

• The genome sequence of the Carline Skipper, Pyrgus carlinae (Rambur, 1839) (Lepidoptera: Hesperiidae).

  PMID 41841042 · PMC12989058 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was generated for a female Pyrgus carlinae specimen (ilPyrCarl1) as part of Project Psyche

  pyrgus pacbio hi-c k-mer

• The genome sequence of the Eastern Rock Grayling, Hipparchia syriaca (Staudinger, 1871) (Lepidoptera: Nymphalidae).

  PMID 41913757 · PMC13033134 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was generated for Hipparchia syriaca (Eastern Rock Grayling) from a female specimen collected in Măcin, Romania

  organism pacbio assembled pacbio hi-c k-mer

• The genome sequence of the Golden Plusia, Polychrysia moneta (Fabricius, 1787) (Lepidoptera: Noctuidae).

  PMID 41938267 · PMC13047365 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was produced for a male Polychrysia moneta specimen as part of Project Psyche.

  moneta assembled haplotype pacbio hi-c k-mer

• The genome sequence of the Common Mummy Wasp, Aleiodes similis (Curtis, 1834) (Hymenoptera: Braconidae).

  PMID 41938269 · PMC13049424 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A genome assembly was generated for an individual female Aleiodes similis (Common Mummy Wasp), containing two haplotypes with total lengths of 280.83 Mb and 284.39 Mb

  aleiodes pacbio hi-c rna-seq

• The genome sequence of the chocolate mining bee, Andrena scotica Perkins, 1916 (Hymenoptera: Andrenidae).

  PMID 41960580 · PMC13058575 · Wellcome open research · 2026 · 7 claims · 8 setups

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  A haploid chromosome-level genome assembly was generated for a male Andrena scotica (chocolate mining bee) specimen.

  andrena pacbio hi-c rna-seq

• The genome sequence of the Northern Grizzled Skipper, Pyrgus centaureae (Rambur, 1839) (Lepidoptera: Hesperiidae).

  PMID 42038589 · PMC13109703 · Wellcome open research · 2026 · 8 claims · 8 setups

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  A chromosome-level genome assembly was produced for Pyrgus centaureae (Northern Grizzled Skipper) as part of Project Psyche.

  pyrgus pacbio hi-c rna-seq