Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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NetworKIN: a resource for exploring cellular phosphorylation networks.
PMID 17981841 · PMC2238868 · Nucleic acids research · 2008 · 8 claims · 4 setups
NetworKIN integrates consensus substrate motifs with probabilistic network context modelling to predict cellular kinase-substrate relations.
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Has reproduction · 98
Integrated omics in Drosophila uncover a circadian kinome.
PMID 32483184 · PMC7264355 · Nature communications · 2020 · 8 claims · 6 setups
iCMod, a computational pipeline integrating transcriptomic, proteomic, and phosphoproteomic circadian data, was developed to accurately identify normalized circadian p-sites (NCPs)
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Has reproduction · 57
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.
PMID 35790189 · PMC9452294 · Nature · 2022 · 8 claims · 8 setups
Apoptotic brown adipocytes release a specific secretome enriched in purine metabolites (including inosine, AMP, hypoxanthine, ATP)
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Phosphoproteomics: new insights into cellular signaling.
PMID 16168091 · PMC1242200 · Genome biology · 2005 · 8 claims · 8 setups
Protein kinases are one of the largest gene families in humans and mice, accounting for 1.7% of the human genome
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Phosphoproteomic analysis of human embryonic stem cells.
PMID 19664994 · PMC2726933 · Cell stem cell · 2009 · 8 claims · 6 setups
MDLC-MS/MS phosphoproteomics identified 2546 phosphorylation sites on 1602 phosphoproteins in undifferentiated hESCs and their differentiated derivatives
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Modification-specific proteomics: strategies for characterization of post-translational modifications using enrichment techniques.
PMID 19743430 · PMC2892724 · Proteomics · 2009 · 8 claims · 8 setups
Lack of efficient enrichment procedures for PTM peptides is a major bottleneck in PTM proteomic research