Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 43
Integration of Dual Stress Transcriptomes and Major QTLs from a Pair of Genotypes Contrasting for Drought and Chronic Nitrogen Starvation Identifies Key Stress Responsive Genes in Rice.
PMID 34089405 · PMC8179884 · Rice (New York, N.Y.) · 2021 · 8 claims · 7 setups
N22 performs better under dual (low N + low water) stress owing to better root architecture, chlorophyll/porphyrin synthesis and oxidative stress management
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EPD in its twentieth year: towards complete promoter coverage of selected model organisms.
PMID 16381980 · PMC1347508 · Nucleic acids research · 2006 · 7 claims · 4 setups
EPD is an annotated, non-redundant collection of experimentally defined eukaryotic POL II promoters accessed via genome position pointers.
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Has reproduction · 75
Genomic regions and candidate genes selected during the breeding of rice in Vietnam.
PMID 35899250 · PMC9309459 · Evolutionary applications · 2022 · 8 claims · 7 setups
XP-CLR and FST scans identify genomic regions with distorted allele frequency/differentiation patterns resulting from differential selective pressures between Vietnamese rice subpopulations
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Has reproduction · 99
A platinum standard pan-genome resource that represents the population structure of Asian rice.
PMID 32265447 · PMC7138821 · Scientific data · 2020 · 6 claims · 6 setups
The 3,000 Rice Genomes (3K-RG) dataset can be subdivided into 15 subpopulations (K=15), refining the previous K=9 population structure.
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Has reproduction · 96
Deep learning based protocol to construct an immune-related gene network of host-pathogen interactions in plants.
PMID 36525344 · PMC9791427 · STAR protocols · 2023 · 6 claims · 6 setups
A deep-learning protocol (DLNet) ranks genes by their contribution to classifying treatment versus control expression data, identifying genes involved in host defense against pathogens.
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Has reproduction · 67
GEMmaker: process massive RNA-seq datasets on heterogeneous computational infrastructure.
PMID 35501696 · PMC9063052 · BMC bioinformatics · 2022 · 6 claims · 3 setups
GEMmaker, an nf-core compliant Nextflow workflow, can quantify gene expression from small to massive RNA-seq datasets while remaining reproducible via versioned containerized software.
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Outlook on Thailand's genomics and computational biology research and development.
PMID 18654621 · PMC2446437 · PLoS computational biology · 2008 · 8 claims · 8 setups
Thai government policy support, infrastructure investment, education programs, and human resource development have substantially advanced genomics and bioinformatics research capacity in Thailand
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When does a protein become an allergen? Searching for a dynamic definition based on most advanced technology tools.
PMID 18477011 · PMC2607534 · Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2008 · 7 claims · 8 setups
IgE-binding is not an intrinsic property of a protein but the result of an interaction between two molecules (antigen and IgE), so a molecule can only be classified relative to demonstrated IgE binding.
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Differentiation of core promoter architecture between plants and mammals revealed by LDSS analysis.
PMID 17855401 · PMC2094075 · Nucleic acids research · 2007 · 7 claims · 8 setups
LDSS analysis identifies octamer sequences with localized distribution profiles as promoter constituents, classifiable into groups (REG, TATA, Inr, Kozak, CpG, Y Patch)
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Proceedings of the First International Conference on Phylogenomics. March 15-19, 2006. Quebec, Canada.
PMID 17288567 · PMC1796603 · BMC evolutionary biology · 2007 · 8 claims · 8 setups
Gene tree parsimony applied to EST data with widespread gene duplication can infer an organismal phylogeny in excellent agreement with the expected angiosperm phylogeny.
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FGF: a web tool for Fishing Gene Family in a whole genome database.
PMID 17584790 · PMC1933194 · Nucleic acids research · 2007 · 6 claims · 3 setups
FGF efficiently searches and identifies gene families in whole-genome databases and outputs visual phylogenetic trees annotated with gene structure, chromosome position, duplication fate, and selective pressure (Ka/Ks)
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Has reproduction · 84
Foster thy young: enhanced prediction of orphan genes in assembled genomes.
PMID 34928390 · PMC9023268 · Nucleic acids research · 2022 · 7 claims · 8 setups
Each of the five gene-prediction pipelines under-predicts orphan genes, with detection as low as 11% under one prediction scenario.
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Diet and DNA.
PMID 15174456 · PMC1315985 · Environmental health perspectives · 2004 · 8 claims · 8 setups
The tombusvirus CIRV p19 protein selectively binds short (21-22 nt) silencing siRNAs, using tryptophan residues Trp39 and Trp42 as molecular 'calipers' that stack with the ends of the siRNA duplex
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Science star over Asia.
PMID 16149850 · PMC1201306 · PLoS biology · 2005 · 8 claims · 7 setups
Ariff Bongso and associates at Singapore's National University Hospital were the first to derive human embryonic stem cells, from a five-day-old discarded human embryo in 1994, and showed the cells were pluripotent with therapeutic transplant potential.
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Large-scale structural analysis of the core promoter in mammalian and plant genomes.
PMID 16049029 · PMC1181242 · Nucleic acids research · 2005 · 8 claims · 7 setups
DNA encodes at least two independent levels of functional information: protein/TF-binding sequence information and physical/structural properties of the molecule itself.
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Evaluation of six methods for estimating synonymous and nonsynonymous substitution rates.
PMID 17127215 · PMC5054070 · Genomics, proteomics & bioinformatics · 2006 · 8 claims · 4 setups
Incorporating more sequence evolution features (transition/transversion bias, nucleotide/codon frequency bias) into Ka/Ks estimation methods yields more accurate and reliable estimates.
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Computing Ka and Ks with a consideration of unequal transitional substitutions.
PMID 16740169 · PMC1552089 · BMC evolutionary biology · 2006 · 7 claims · 7 setups
MYN, a modified version of the Yang-Nielsen (YN) algorithm based on the Tamura-Nei Model, allows unequal transitional substitution rates between purines (κR) and pyrimidines (κY) plus codon frequency bias
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Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma.
PMID 17344319 · PMC1874664 · Nucleic acids research · 2007 · 7 claims · 7 setups
aPRIMES is a novel array-based method that detects direct (absolute) methylation status of CGIs via competitive hybridization of McrBC-digested (methylated) versus HpaII/BstUI-digested (unmethylated) DNA from the same genome, avoiding reference-tissue and copy-number biases
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Genomics in space life sciences.
PMID 18558380 · PMC5054090 · Genomics, proteomics & bioinformatics · 2008 · 8 claims · 6 setups
Sudden changes in gravity alter mRNA levels of various genes, indicating molecular-level effects of microgravity
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Nucleosome deposition and DNA methylation at coding region boundaries.
PMID 19723310 · PMC2768978 · Genome biology · 2009 · 8 claims · 8 setups
Nucleosomes and DNA methylation form distinct peaks just downstream of the start codon and just upstream of the stop codon, marking both ends of protein coding units genome-wide.