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26 matching publication(s)
Targeting the epigenome and the integrated stress response to normalize colorectal cancer subclonal plasticity and progression.
PMID 41963303 · Cell Death Dis · 2026
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Single-cell protein activity analysis reveals aberrant myogenesis and IGF2-PI3K pathway dependencies in MYOD1-mutant rhabdomyosarcoma.
PMID 41758938 · Sci Adv · 2026
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Covalent binding of thioredoxin to TXNIP is required for diet-induced insulin resistance in the liver.
PMID 40345590 · J Biol Chem · 2025
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The Drosophila estrogen-related receptor promotes triglyceride storage within the larval fat body.
PMID 40288680 · J Lipid Res · 2025
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RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia.
PMID 39820365 · Nat Commun · 2025
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Community assessment of methods to deconvolve cellular composition from bulk gene expression.
PMID 39191725 · Nat Commun · 2024
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An atlas of the human liver diurnal transcriptome and its perturbation by hepatitis C virus infection.
PMID 39209804 · Nat Commun · 2024
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Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists.
PMID 37906287 · J Clin Invest · 2024
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.
PMID 37572656 · Immunity · 2023
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iBRIDGE: A Data Integration Method to Identify Inflamed Tumors from Single-cell RNA-Seq Data and Differentiate Cell Type-Specific Markers of Immune-Cell Infiltr
PMID 37023414 · Cancer Immunol Res · 2023
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Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity.
PMID 36928603 · Nat Genet · 2023
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Microglia-containing cerebral organoids derived from induced pluripotent stem cells for the study of neurological diseases.
PMID 36936782 · iScience · 2023
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74/100
A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients.
PMID 36694043 · Commun Biol · 2023
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The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2.
PMID 36627412 · Cell Mol Life Sci · 2023
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Transcriptomics, regulatory syntax, and enhancer identification in mesoderm-induced ESCs at single-cell resolution.⚑
PMID 35977485 · Cell Rep · 2022
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TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes.
PMID 35580127 · PLoS Genet · 2022
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Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection.
PMID 35025971 · PLoS Pathog · 2022
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Monocarboxylate Transporter-2 Expression Restricts Tumor Growth in a Murine Model of Lung Cancer: A Multi-Omic Analysis.⚑
PMID 34638954 · Int J Mol Sci · 2021
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DeepProg: an ensemble of deep-learning and machine-learning models for prognosis prediction using multi-omics data.
PMID 34261540 · Genome Med · 2021
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Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathway
PMID 34095875 · Cell Rep Med · 2021
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PredTAD: A machine learning framework that models 3D chromatin organization alterations leading to oncogene dysregulation in breast cancer cell lines.
PMID 34093998 · Comput Struct Biotechnol J · 2021
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Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression.
PMID 33722289 · Genome Biol · 2021
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In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.
PMID 32898168 · PLoS Biol · 2020
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Wx: a neural network-based feature selection algorithm for transcriptomic data.
PMID 31324856 · Sci Rep · 2019
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An open RNA-Seq data analysis pipeline tutorial with an example of reprocessing data from a recent Zika virus study.
PMID 27583132 · F1000Res · 2016
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