Adam L. MacLean
Reproducibility track record
1
assessed papers
90/100
mean reproducibility
1
reproduced (C1–C2)
0
flagged
8
total citations
flag rate:
0%
(0/1)
The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.
Authorship role
first author: 0
last author: 1
Topics
Funders
—
Frequent co-authors
Institutions
University of Southern California 1
Geography (author institutions)
US 1
Co-author network
Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.
How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.
Assessed papers (1)
Complete publication record (139)
Request a reproduction →1 assessed by us (1 reproduced) · 138 not yet assessed — every PubMed paper on record, linked below.
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A class act: HDAC1- Malat1 regulates MDSC apoptosis and cell cycling to decrease suppression of T cells ↗bioRxiv (Cold Spring Harbor Laboratory) · 2026 · PMID 41929180not yet assessed
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Longitudinal Single-Cell RNA-Sequencing Reveals Evolution of Micro- and Macro-states in Chronic Myeloid Leukemia ↗Cancer Research · 2026 · PMID 40661452not yet assessed
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Inference of marker genes of subtle cell state changes via iLR: iterative logistic regression ↗Bioinformatics · 2026 · PMID 41627891not yet assessed
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Abstract 6830: State-transition model of time-series single-cell RNA-seq identifies gene-level origins of disease microstate stability in chronic myeloid leukemia (CML). ↗Cancer Research · 2026not yet assessed
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A Mecom—Cdk6 toggle switch governs hematopoietic stem-to-multipotent fate transitions via distinct multistable landscapes ↗bioRxiv (Cold Spring Harbor Laboratory) · 2026 · PMID 42427749not yet assessed
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Immune Circuit Rewiring by HDAC Inhibition Enables Response to Dual Checkpoint Blockade in Metastatic Breast Cancer ↗Cancer Research · 2026 · PMID 42578817not yet assessed
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Modeling the dynamics of EMT reveals genes associated with pan-cancer intermediate states and plasticity ↗npj Systems Biology and Applications · 2025 · PMID 40210876not yet assessed
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Data-driven model discovery and model selection for noisy biological systems ↗PLoS Computational Biology · 2025 · PMID 39836686not yet assessed
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Transition paths across the epithelial-mesenchymal transition landscape are dictated by network logic ↗Development · 2025 · PMID 40395204not yet assessed
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Gene regulatory network inference with popInfer reveals the dynamic regulation of hematopoietic stem cell quiescence ↗iScience · 2025 · PMID 41488354not yet assessed
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Inference of marker genes of subtle cell state changes via iterative logistic regression ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025not yet assessed
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Abstract B020: Dual checkpoint inhibition using anti-PD-1 and anti-CTLA-4 in combination with entinostat increases treatment efficacy and decreases suppressive signaling between myeloid cells and T cells in breast-to-lung metastasis ↗Cancer Immunology Research · 2025not yet assessed
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Abstract A068: HDAC1 and HDAC3 inhibition decreases myeloid derived suppressor cell function through STAT3-mediated apoptosis ↗Cancer Immunology Research · 2025not yet assessed
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The RNA Exosome Maintains Cellular RNA Homeostasis by Controlling Transcript Abundance in the Brain ↗SSRN Electronic Journal · 2025not yet assessed
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Cancer systems immunology reveals myeloid—T cell interactions and B cell activation mediate response to checkpoint inhibition in metastatic breast cancer ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 40661534not yet assessed
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Abstract P1-04-21: Suppressing suppression: histone deacetylase inhibition primes the metastatic tumor microenvironment to respond to checkpoint inhibition by dynamic rewiring of cell interactions ↗Clinical Cancer Research · 2025not yet assessed
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Beyond RECIST: mathematical modeling and Bayesian inference reveal the importance of immune suppressive parameters in metastatic breast cancer ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 40832320not yet assessed
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735 T cell interactions and B cell activation mediate response to treatment with entinostat and checkpoint inhibitors in metastatic breast cancer ↗Regular and Young Investigator Award Abstracts · 2025not yet assessed
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Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in lifeNature Communications · 2024 · PMID 39592593L1 90/100
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Gastrulation-stage gene expression in Nipbl +/− mouse embryos foreshadows the development of syndromic birth defects ↗Science Advances · 2024 · PMID 38507484not yet assessed
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A new Neu—a syngeneic model of spontaneously metastatic HER2-positive breast cancer ↗Clinical & Experimental Metastasis · 2024 · PMID 38717519not yet assessed
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Hematopoietic stem cell aging by the niche ↗Blood · 2024 · PMID 39052267not yet assessed
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Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024 · PMID 38496542not yet assessed
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Modeling the dynamics of EMT reveals genes associated with pan-cancer intermediate states and plasticity ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024not yet assessed
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Data-driven model discovery and model selection for noisy biological systems ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024not yet assessed
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Intratumoral CXCL12 Gradients Contextualize Tumor Cell Invasion, Migration and Immune Suppression in Breast Cancer ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024 · PMID 39464015not yet assessed
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Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2 + breast cancer ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024 · PMID 38352476not yet assessed
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Abstract 6522: Epigenetic modulation decreases myeloid suppression to improve response to immune checkpoint inhibition in breast cancer ↗Cancer Research · 2024not yet assessed
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The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brain ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024 · PMID 39554067not yet assessed
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770 Entinostat attenuates myeloid cell immunosuppression and increases the efficacy of checkpoint inhibition in a HER2+ mouse model of breast-to-lung metastasis ↗Regular and Young Investigator Award Abstracts · 2024not yet assessed
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874 Epigenetic modulation of myeloid derived suppressor cells decreases suppressive signaling through the STAT3 pathway ↗Regular and Young Investigator Award Abstracts · 2024not yet assessed
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Transition paths across the EMT landscape are dictated by network logic ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024 · PMID 39677780not yet assessed
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Exploring Stem Cells: A Hands-On Approach to Elementary STEM Education ↗Connected Science Learning · 2024not yet assessed
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Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis ↗Science Advances · 2023 · PMID 37418531not yet assessed
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Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney ↗Developmental Cell · 2023 · PMID 37673062not yet assessed
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Myeloid-Derived Suppressor–Cell Dynamics Control Outcomes in the Metastatic Niche ↗Cancer Immunology Research · 2023 · PMID 36848523not yet assessed
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The Coming of Age of Nucleic Acid Vaccines during COVID-19 ↗mSystems · 2023 · PMID 36263086not yet assessed
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Application of Traditional Vaccine Development Strategies to SARS-CoV-2 ↗mSystems · 2023 · PMID 36034485not yet assessed
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Single-cell Ca2+ parameter inference reveals how transcriptional states inform dynamic cell responses ↗Journal of The Royal Society Interface · 2023 · PMID 37282589not yet assessed
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Sex differences in proximal tubule metabolism influence hemodynamics and salt reabsorption to mediate dimorphic susceptibility to kidney diseases ↗Physiology · 2023not yet assessed
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Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37131694not yet assessed
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Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence upon diet restriction and aging ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37131596not yet assessed
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Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37205355not yet assessed
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Gastrulation-stage gene expression in Nipbl +/- mouse embryos foreshadows the development of syndromic birth defects ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37905011not yet assessed
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Julia for biologists ↗Nature Methods · 2023 · PMID 37024649not yet assessed
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Voices carry ↗Nature Chemical Biology · 2023 · PMID 36635562not yet assessed
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Abstract 5167: Entinostat's modulation of myeloid derived suppressor cells through the STAT3-NFκB-AP-1 axis decreases suppressive signaling ↗Cancer Research · 2023not yet assessed
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Abstract 3256: Entinostat enhances the efficacy of checkpoint inhibition in breast-to-lung metastases and is associated with alterations in the phenotype and function of myeloid cell populations ↗Cancer Research · 2023not yet assessed
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Author Correction: Julia for biologists ↗Nature Methods · 2023 · PMID 37120675not yet assessed
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Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice ↗Blood · 2022 · PMID 35231105not yet assessed
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Profiling intermediate cell states in high resolution ↗Cell Reports Methods · 2022 · PMID 35497492not yet assessed
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Correction for Rando et al., “Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure” ↗mSystems · 2022 · PMID 35076276not yet assessed
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Single-cell Ca 2+ parameter inference reveals how transcriptional states inform dynamic cell responses ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
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Myeloid-derived suppressor cell dynamics control outcomes in the metastatic niche ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
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Single-cell transcriptomic analysis of zebrafish cranial neural crest reveals spatiotemporal regulation of lineage decisions during development ↗Cell Reports · 2021 · PMID 34936864not yet assessed
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RVAgene: generative modeling of gene expression time series data ↗Bioinformatics · 2021 · PMID 33974008not yet assessed
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A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis ↗Development · 2021 · PMID 34935903not yet assessed
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Modeling the effects of EMT-immune dynamics on carcinoma disease progression ↗Communications Biology · 2021 · PMID 34408236not yet assessed
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Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure ↗mSystems · 2021 · PMID 33594340not yet assessed
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Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure ↗arXiv (Cornell University) · 2021not yet assessed
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A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis ↗bioRxiv (Cold Spring Harbor Laboratory) · 2021not yet assessed
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Forcing cells to change lineages by cell-cell communication2021not yet assessed
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The diverse landscape of modeling in single-cell biology ↗Physical Biology · 2021 · PMID 34283805not yet assessed
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drbergman/tumor-immune-emt-code: Tumor-Immune-EMT Code ↗Zenodo (CERN European Organization for Nuclear Research) · 2021not yet assessed
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Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics ↗Cell Reports · 2020 · PMID 32187560not yet assessed
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Single cell transcriptomics of human epidermis identifies basal stem cell transition states ↗Nature Communications · 2020 · PMID 32843640not yet assessed
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RVAgene: Generative modeling of gene expression time series data ↗bioRxiv (Cold Spring Harbor Laboratory) · 2020not yet assessed
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Cell lineage and communication network inference via optimization for single-cell transcriptomics ↗Nucleic Acids Research · 2019 · PMID 30923815not yet assessed
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Defining epidermal basal cell states during skin homeostasis and wound healing using single-cell transcriptomics ↗bioRxiv (Cold Spring Harbor Laboratory) · 2019not yet assessed
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Single cell transcriptomics of human epidermis reveals basal stem cell transition states ↗bioRxiv (Cold Spring Harbor Laboratory) · 2019not yet assessed
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Defining Epidermal Basal Cell States During Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics ↗SSRN Electronic Journal · 2019not yet assessed
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Modeling the effects of EMT-immune dynamics on epithelial cancer progression ↗bioRxiv (Cold Spring Harbor Laboratory) · 2019not yet assessed
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scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data ↗Bioinformatics · 2018 · PMID 29415263not yet assessed
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Exploring intermediate cell states through the lens of single cells ↗Current Opinion in Systems Biology · 2018 · PMID 30450444not yet assessed
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Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis ↗Journal of Mathematical Biology · 2018 · PMID 29392399not yet assessed
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An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation ↗EMBO Reports · 2018 · PMID 30413481not yet assessed
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Transcriptomics reveals complex kinetics of dorsal–ventral patterning gene expression in the mandibular arch ↗genesis · 2018 · PMID 30561090not yet assessed
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1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia ↗Journal of Investigative Dermatology · 2018not yet assessed
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1337 Single cell transcriptome profiling of human interfollicular epidermis reveals robust heterogeneity and divergent differentiation lineages ↗Journal of Investigative Dermatology · 2018not yet assessed
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Multiscale Modeling of Inflammation-Induced Tumorigenesis Reveals Competing Oncogenic and Oncoprotective Roles for Inflammation ↗Cancer Research · 2017 · PMID 28951462not yet assessed
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A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions ↗BMC Systems Biology · 2017 · PMID 28511648not yet assessed
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Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection ↗Stem Cells · 2017 · PMID 28833970not yet assessed
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Cell Lineage and Communication Network Inference via Optimization for Single-cell Transcriptomics ↗bioRxiv (Cold Spring Harbor Laboratory) · 2017not yet assessed
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Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis ↗bioRxiv (Cold Spring Harbor Laboratory) · 2017not yet assessed
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LB999 Role of transcription factor Ovol2 in skin epithelial regeneration and repair ↗Journal of Investigative Dermatology · 2017not yet assessed
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Additional file 1: of A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions ↗Figshare · 2017not yet assessed
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Additional file 1: of A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions ↗Figshare · 2017not yet assessed
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Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis ↗Stem Cells · 2016 · PMID 27671750not yet assessed
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Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia ↗Journal of Theoretical Biology · 2016 · PMID 27130539not yet assessed
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Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points ↗Open Biology · 2016 · PMID 27335321not yet assessed
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Single Cell Phenotyping Reveals Heterogeneity among Haematopoietic Stem Cells Following Infection ↗bioRxiv (Cold Spring Harbor Laboratory) · 2016not yet assessed
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Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis: Stem Cell Population Biology2016not yet assessed
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Parameter-free methods distinguish Wnt pathway models and guide design of experiments ↗Proceedings of the National Academy of Sciences · 2015 · PMID 25730853not yet assessed
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Conditional random matrix ensembles and the stability of dynamical systems ↗Apollo (University of Cambridge) · 2015not yet assessed
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Cellular population dynamics control the robustness of the stem cell niche ↗Biology Open · 2015 · PMID 26453624not yet assessed
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Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study ↗Methods in molecular biology · 2015 · PMID 26677193not yet assessed
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Cellular Population Dynamics Control the Robustness of the Stem Cell Niche ↗bioRxiv (Cold Spring Harbor Laboratory) · 2015not yet assessed
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Mathematical and Statistical Techniques for Systems Medicine: The Wnt\n Signaling Pathway as a Case Study ↗arXiv (Cornell University) · 2015not yet assessed
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The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia ↗Proceedings of the National Academy of Sciences · 2014 · PMID 24567385not yet assessed
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Epithelial-Mesenchymal Transition in Metastatic Cancer Cell Populations Affects Tumor Dormancy in a Simple Mathematical Model ↗Biomedicines · 2014 · PMID 28548077not yet assessed
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Modelling haematopoietic stem cells in their niche ↗Spiral (Imperial College London) · 2014not yet assessed
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Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled ↗Journal of The Royal Society Interface · 2013 · PMID 23349436not yet assessed
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A comparison of canonical discriminant analysis and principal component analysis for spectral transformation.Photogrammetric Engineering & Remote Sensing · 2000not yet assessed
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ON SOME UNUSUAL FORMS OF EPIDEMIC DISEASE. ↗The Lancet · 1918not yet assessed
Full bibliography from OpenAlex; reproducibility verdicts matched by PMID.
Author attribution follows OpenAlex disambiguation, which is imperfect — a researcher's papers can be split across profiles or mixed with a namesake.
Merged across profiles sharing this ORCID where present. See every “MacLean A” paper on PubMed ↗