Saswata Talukdar

The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.

Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.

How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.

Assessed papers (1)

• FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues
  2016 L1 No computation

1 assessed by us (0 reproduced) · 69 not yet assessed — every PubMed paper on record, linked below.

• CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly ↗

  Nature · 2026 · PMID 41741636
  not yet assessed
• AI-assisted fibrosis scoring in MASH: Exploring pathologist decision-making with an SHG-based AI digital pathology tool ↗

  JHEP Reports · 2026 · PMID 41825098
  not yet assessed
• LC-MS measurement of triglyceride hydrolysis: Application in studies of Patatin-like phospholipase domain-containing protein 3 activity ↗

  Analytical Biochemistry · 2026 · PMID 41839402
  not yet assessed
• AI digital pathology as a key tool providing in-depth understanding of the progression and regression of MASH and fibrosis in male mouse models ↗

  Nature Communications · 2026 · PMID 42486853
  not yet assessed
• Loss of mitochondrial amidoxime-reducing component 1 (mARC1) prevents disease progression by reducing fibrosis in multiple mouse models of chronic liver disease ↗

  Hepatology Communications · 2025 · PMID 39927988
  not yet assessed
• A mitochondrial amidoxime-reducing component 1 (mARC1) A168T amino acid substitution does not confer protection from MASH and fibrosis in multiple mouse models of chronic liver disease ↗

  Biochemical Journal · 2025 · PMID 41428769
  not yet assessed
• Whole body and hematopoietic cell-specific deletion of G-protein coupled receptor 65 (GPR65) improves insulin sensitivity in diet-induced obese mice ↗

  Molecular Metabolism · 2025 · PMID 40389090
  not yet assessed
• Lc-Ms Measurement of Triglyceride Hydrolysis: Application in Studies of Patatin-Like Phospholipase Domain-Containing Protein 3 Activity ↗

  SSRN Electronic Journal · 2025
  not yet assessed
• Utility of AI digital pathology as an aid for pathologists scoring fibrosis in MASH ↗

  Journal of Hepatology · 2024 · PMID 39612947
  not yet assessed
• CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2024 · PMID 38895340
  not yet assessed
• THU-198 In vitro and in vivo pharmacological characterization of human PNPLA3-targeting short interfering RNA molecules for the treatment of metabolic dysfunction-associated steatohepatitis ↗

  Journal of Hepatology · 2024
  not yet assessed
• FGF21 via mitochondrial lipid oxidation promotes physiological vascularization in a mouse model of Phase I ROP ↗

  Angiogenesis · 2023 · PMID 36943533
  not yet assessed
• Leukotriene B4 receptor 1 does not mediate disease progression in a mouse model of liver fibrosis ↗

  Biochemical Journal · 2023 · PMID 38014500
  not yet assessed
• Supplementary Material for: Regulation of macrophage cell surface GAPDH alters LL-37 internalization and downstream effects in the cell ↗

  Figshare · 2023
  not yet assessed
• Omega-3/Omega-6 Long-Chain Fatty Acid Imbalance in Phase I Retinopathy of Prematurity ↗

  Nutrients · 2022 · PMID 35405946
  not yet assessed
• Using measures of metabolic flux to align screening and clinical development: Avoiding pitfalls to enable translational studies ↗

  SLAS DISCOVERY · 2022 · PMID 35058172
  not yet assessed
• Loss of low-molecular-weight protein tyrosine phosphatase shows limited improvement in glucose tolerance but causes mild cardiac hypertrophy in mice ↗

  American Journal of Physiology-Endocrinology and Metabolism · 2022 · PMID 35403438
  not yet assessed
• Discovery of a new class of integrin antibodies for fibrosis ↗

  Scientific Reports · 2021 · PMID 33483531
  not yet assessed
• Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa ↗

  Experimental & Molecular Medicine · 2021 · PMID 34799683
  not yet assessed
• Retinal glial remodeling by FGF21 preserves retinal function during photoreceptor degeneration ↗

  iScience · 2021 · PMID 33937726
  not yet assessed
• Vitreous metabolomics profiling of proliferative diabetic retinopathy ↗

  Diabetologia · 2020 · PMID 33099660
  not yet assessed
• FGF19 and FGF21: In NASH we trust ↗

  Molecular Metabolism · 2020 · PMID 33383173
  not yet assessed
• Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity ↗

  Cell Metabolism · 2020 · PMID 32413335
  not yet assessed
• Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis ↗

  Cell Reports Medicine · 2020 · PMID 33205063
  not yet assessed
• Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models ↗

  International Journal of Molecular Sciences · 2020 · PMID 32054022
  not yet assessed
• Inhibition of Grb14, a negative modulator of insulin signaling, improves glucose homeostasis without causing cardiac dysfunction ↗

  Scientific Reports · 2020 · PMID 32099031
  not yet assessed
• Free fatty acid receptor 4 activation protects against choroidal neovascularization in mice ↗

  Angiogenesis · 2020 · PMID 32140799
  not yet assessed
• Mapping Lipogenic Flux: A Gold LDI–MS Approach for Imaging Neutral Lipid Kinetics ↗

  Journal of the American Society for Mass Spectrometry · 2020 · PMID 32840373
  not yet assessed
• GPR105 Ablation Prevents Inflammation and Improves Insulin Sensitivity in Mice with Diet-Induced Obesity ↗

  Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2020
  not yet assessed
• Discovery of A New Class of Integrin Antibodies for Fibrosis ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease ↗

  Journal of Clinical Investigation · 2019 · PMID 31805015
  not yet assessed
• Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice ↗

  Diabetes · 2018 · PMID 29487115
  not yet assessed
• Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing ↗

  Scientific Reports · 2018 · PMID 29523796
  not yet assessed
• FGF21 restores photoreceptor function in type 1 diabetic mice

  Investigative Ophthalmology & Visual Science · 2018
  not yet assessed
• Photoreceptor glucose metabolic modulation by adiponectin prevents hyperglycemic ROP

  Investigative Ophthalmology & Visual Science · 2018
  not yet assessed
• Once‐weekly administration of a long‐acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese people with hypertriglyceridaemia and in non‐human primates ↗

  Diabetes Obesity and Metabolism · 2017 · PMID 28573777
  not yet assessed
• FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice ↗

  Cell Reports · 2017 · PMID 28199833
  not yet assessed
• Photoreceptor glucose metabolism determines normal retinal vascular growth ↗

  EMBO Molecular Medicine · 2017 · PMID 29180355
  not yet assessed
• FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis ↗

  Molecular Metabolism · 2017 · PMID 28580278
  not yet assessed
• Fibroblast growth factor 21 administration suppresses pathologic retinal vessel growth in oxygen-induced retinopathy

  Investigative Ophthalmology & Visual Science · 2017
  not yet assessed
• A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects ↗

  Cell Metabolism · 2016 · PMID 26959184
  not yet assessed
• FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues

  Cell Metabolism · 2016 · PMID 26853749
  L1 No computation
• PF-05231023, a long-acting FGF21 analogue, decreases body weight by reduction of food intake in non-human primates ↗

  Journal of Pharmacokinetics and Pharmacodynamics · 2016 · PMID 27405817
  not yet assessed
• FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues ↗

  Atherosclerosis · 2016
  not yet assessed
• FGF21 Regulates Sweet and Alcohol Preference ↗

  Cell Metabolism · 2015 · PMID 26724861
  not yet assessed
• LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes ↗

  Nature Medicine · 2015 · PMID 25706874
  not yet assessed
• Pharmacokinetics (PK), Pharmacodynamics (PD) and Integrated PK/PD Modeling of a Novel Long Acting FGF21 Clinical Candidate PF-05231023 in Diet-Induced Obese and Leptin-Deficient Obese Mice ↗

  PLoS ONE · 2015 · PMID 25790234
  not yet assessed
• FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance ↗

  Scientific Reports · 2015 · PMID 26153793
  not yet assessed
• Fibroblast Growth Factor 21 Improves Insulin Sensitivity and Synergizes with Insulin in Human Adipose Stem Cell-Derived (hASC) Adipocytes ↗

  PLoS ONE · 2014 · PMID 25365322
  not yet assessed
• Knock-Down of IL-1Ra in Obese Mice Decreases Liver Inflammation and Improves Insulin Sensitivity ↗

  PLoS ONE · 2014 · PMID 25244011
  not yet assessed
• NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids ↗

  Cell · 2013 · PMID 24074869
  not yet assessed
• Development of a Novel Long-Acting Antidiabetic FGF21 Mimetic by Targeted Conjugation to a Scaffold Antibody ↗

  Journal of Pharmacology and Experimental Therapeutics · 2013 · PMID 23720456
  not yet assessed
• Neuronal Sirt1 Deficiency Increases Insulin Sensitivity in Both Brain and Peripheral Tissues ↗

  Journal of Biological Chemistry · 2013 · PMID 23457303
  not yet assessed
• Correction: GPR105 Ablation Prevents Inflammation and Improves Insulin Sensitivity in Mice with Diet-Induced Obesity ↗

  The Journal of Immunology · 2013
  not yet assessed
• Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase ↗

  Nature Medicine · 2012 · PMID 22863787
  not yet assessed
• Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3 ↗

  Cell Metabolism · 2012 · PMID 22958918
  not yet assessed
• GPR105 Ablation Prevents Inflammation and Improves Insulin Sensitivity in Mice with Diet-Induced Obesity ↗

  The Journal of Immunology · 2012 · PMID 22778393
  not yet assessed
• G protein–coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice ↗

  Journal of Clinical Investigation · 2012 · PMID 22653059
  not yet assessed
• Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet–Induced Insulin Resistance ↗

  Diabetes · 2011 · PMID 21911747
  not yet assessed
• Increased Macrophage Migration Into Adipose Tissue in Obese Mice ↗

  Diabetes · 2011 · PMID 22190646
  not yet assessed
• Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity ↗

  Cell · 2011 · PMID 22078880
  not yet assessed
• Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases ↗

  Trends in Pharmacological Sciences · 2011 · PMID 21663979
  not yet assessed
• Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones ↗

  Nature Medicine · 2011 · PMID 21532596
  not yet assessed
• Adipocyte NCoR Knockout Decreases PPARg Phosphorylation and Enhances PPARg Activity and Insulin Sensitivity

  2011
  not yet assessed
• GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects ↗

  Cell · 2010 · PMID 20813258
  not yet assessed
• Osteopontin Is Required for the Early Onset of High Fat Diet-Induced Insulin Resistance in Mice ↗

  PLoS ONE · 2010 · PMID 21103061
  not yet assessed
• The role of the ERK MAP kinase pathway in CD4 T cell proliferation and differentiation ↗

  The FASEB Journal · 2008
  not yet assessed
• Chenodeoxycholic acid suppresses the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317 ↗

  Journal of Lipid Research · 2007 · PMID 17823458
  not yet assessed
• The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317 ↗

  Journal of Lipid Research · 2006 · PMID 16931873
  not yet assessed
• Analysis of the mechanisms mediating the regulation of acetyl -CoA carboxylase transcription by the liver X receptor and chenodeoxycholic acid ↗

  2006
  not yet assessed