Martin Brenner

The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.

Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.

How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.

Assessed papers (1)

• FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues
  2016 L1 No computation

1 assessed by us (0 reproduced) · 50 not yet assessed — every PubMed paper on record, linked below.

• 3071-LB: Treatment of Obese Nonhuman Primates with an Activin E Antibody Leads to Fat-Selective Improvement in Body Composition ↗

  Diabetes · 2026
  not yet assessed
• From the shoot to the rhizosphere: The short-term cascade impact of aerial microplastic ↗

  Environmental and Experimental Botany · 2025
  not yet assessed
• Hesperetin Protects from Palmitic-Acid-Induced Lipotoxicity through the Inhibition of Glutaminolysis, mTORC1 Signaling, and Limited Apoptosis ↗

  Journal of Agricultural and Food Chemistry · 2025 · PMID 40838694
  not yet assessed
• Machine learning and data-driven inverse modeling of metabolomics unveil key processes of active aging ↗

  npj Systems Biology and Applications · 2025 · PMID 40993122
  not yet assessed
• Sulforaphane impedes mitochondrial reprogramming and histone acetylation in polarizing M1 (LPS) macrophages ↗

  Free Radical Biology and Medicine · 2024 · PMID 38301976
  not yet assessed
• Corrigendum: Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages ↗

  Frontiers in Immunology · 2024 · PMID 38711502
  not yet assessed
• Machine learning and data-driven inverse modeling of metabolomics unveil key process of active aging ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2024
  not yet assessed
• Machine learning and data-driven inverse modeling of metabolomics unveil key process of active aging ↗

  Research Square · 2024
  not yet assessed
• Metabolic support by macrophages sustains colonic epithelial homeostasis ↗

  Cell Metabolism · 2023 · PMID 37804836
  not yet assessed
• Norbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFκB, MAPK and STAT3 activation and blocking metabolic reprogramming ↗

  Frontiers in Immunology · 2023 · PMID 37251401
  not yet assessed
• Branched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming ↗

  Frontiers in Immunology · 2022 · PMID 36311795
  not yet assessed
• Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages ↗

  Frontiers in Immunology · 2022 · PMID 35983049
  not yet assessed
• Identification of apple cultivars hypoallergenic for birch pollen‐allergic individuals by a multidisciplinary in vitro and in vivo approach ↗

  Clinical and Translational Allergy · 2022 · PMID 36036236
  not yet assessed
• Local and systemic metabolic adjustments to drought in maize: Hydraulic redistribution in a split‐root system ↗

  Journal of Plant Nutrition and Soil Science · 2022
  not yet assessed
• A Potential Citrate Shunt in Erythrocytes of PKAN Patients Caused by Mutations in Pantothenate Kinase 2 ↗

  Biomolecules · 2022 · PMID 35204826
  not yet assessed
• Branched-Chain Ketoacids Derived from Cancer Cells Modulate Macrophage Polarization and Metabolic Reprogramming ↗

  SSRN Electronic Journal · 2022
  not yet assessed
• Root exudation of contrasting drought-stressed pearl millet genotypes conveys varying biological nitrification inhibition (BNI) activity ↗

  Biology and Fertility of Soils · 2021 · PMID 35399158
  not yet assessed
• Dissecting Metabolism of Leaf Nodules in Ardisia crenata and Psychotria punctata ↗

  Frontiers in Molecular Biosciences · 2021 · PMID 34395523
  not yet assessed
• A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects ↗

  Cell Metabolism · 2016 · PMID 26959184
  not yet assessed
• Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance ↗

  Cell · 2016 · PMID 27814523
  not yet assessed
• FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues

  Cell Metabolism · 2016 · PMID 26853749
  L1 No computation
• FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues ↗

  Atherosclerosis · 2016
  not yet assessed
• Pharmacokinetics (PK), Pharmacodynamics (PD) and Integrated PK/PD Modeling of a Novel Long Acting FGF21 Clinical Candidate PF-05231023 in Diet-Induced Obese and Leptin-Deficient Obese Mice ↗

  PLoS ONE · 2015 · PMID 25790234
  not yet assessed
• FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance ↗

  Scientific Reports · 2015 · PMID 26153793
  not yet assessed
• Fibroblast Growth Factor 21 Improves Insulin Sensitivity and Synergizes with Insulin in Human Adipose Stem Cell-Derived (hASC) Adipocytes ↗

  PLoS ONE · 2014 · PMID 25365322
  not yet assessed
• Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion ↗

  American Journal of Physiology-Endocrinology and Metabolism · 2013 · PMID 24085034
  not yet assessed
• Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example ↗

  ACS Medicinal Chemistry Letters · 2013 · PMID 24900608
  not yet assessed
• Novel Pancreatic Endocrine Maturation Pathways Identified by Genomic Profiling and Causal Reasoning ↗

  PLoS ONE · 2013 · PMID 23418498
  not yet assessed
• Langzeiteffekt eines interdisziplinären 52-wöchigen Gewichtsreduktionsprogramms auf Adipokine und die nichtalkoholische Fettlebererkrankung in adipösen Patienten - Eine prospektive Auswertung ↗

  Aktuelle Ernährungsmedizin · 2013
  not yet assessed
• Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase ↗

  Nature Medicine · 2012 · PMID 22863787
  not yet assessed
• Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists ↗

  ACS Medicinal Chemistry Letters · 2012 · PMID 24900564
  not yet assessed
• Optimization of triazole-based TGR5 agonists towards orally available agents ↗

  MedChemComm · 2012
  not yet assessed
• Engineering and characterization of the long‐acting glucagon‐like peptide‐1 analogue LY2189265, an Fc fusion protein ↗

  Diabetes/Metabolism Research and Reviews · 2010 · PMID 20503261
  not yet assessed
• Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets ↗

  Diabetes · 2010 · PMID 20823098
  not yet assessed
• A novel role of bone morphogenetic protein-6 (BMP-6) as an endocrine regulator of bone and glucose homeostasis ↗

  Bone · 2010
  not yet assessed
• Fibroblast Growth Factor-21 Improves Pancreatic β-Cell Function and Survival by Activation of Extracellular Signal–Regulated Kinase 1/2 and Akt Signaling Pathways ↗

  Diabetes · 2006 · PMID 16936195
  not yet assessed
• Activation of Liver X Receptors and Retinoid X Receptors Induces Growth Arrest and Apoptosis in Insulin-Secreting Cells ↗

  Endocrinology · 2006 · PMID 17194744
  not yet assessed
• Sterol Regulatory Element-Binding Protein 1 Mediates Liver X Receptor-β-Induced Increases in Insulin Secretion and Insulin Messenger Ribonucleic Acid Levels ↗

  Endocrinology · 2006 · PMID 16644917
  not yet assessed
• A Novel Glucokinase Activator Modulates Pancreatic Islet and Hepatocyte Function ↗

  Endocrinology · 2005 · PMID 15919746
  not yet assessed
• Hepatic and glucagon-like peptide-1–mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors ↗

  Journal of Clinical Investigation · 2004 · PMID 15173883
  not yet assessed
• Hepatic and glucagon-like peptide-1–mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors ↗

  Journal of Clinical Investigation · 2004
  not yet assessed
• A buffer temperature controlled perifusion system to study temperature dependence and kinetics of insulin secretion in MIN6 pseudoislets ↗

  Journal of Pharmacological and Toxicological Methods · 2004 · PMID 15233968
  not yet assessed
• Einfluss verschiedener Sekretagoga auf die Insulinfreisetzung

  2002
  not yet assessed
• A novel herpes vector for the high efficiency transduction of primary hematopoietic cells ↗

  European Journal of Cancer · 1997
  not yet assessed
• ChemInform Abstract: Dopamine Agonists Related to 3‐Allyl‐6‐chloro‐2,3,4,5‐tetrahydro‐1‐(4‐ hydroxyphenyl)‐1H‐3‐benzazepine‐7,8‐diol. 6‐Position Modifications. ↗

  ChemInform · 1987
  not yet assessed
• ChemInform Abstract: Dopamine Receptor Agonists: 3‐Allyl‐6‐chloro‐2,3,4,5‐tetrahydro‐1‐(4‐ hydroxyphenyl)‐1H‐3‐benzazepine‐7,8‐diol and a Series of Related 3‐Benzazepines. ↗

  ChemInform · 1986
  not yet assessed
• Synthesis, resolution, absolute stereochemistry, and enantioselectivity of 3',4'-dihydroxynomifensine ↗

  Journal of Medicinal Chemistry · 1984 · PMID 6317860
  not yet assessed
• ChemInform Abstract: SYNTHESIS, RESOLUTION, ABSOLUTE STEREOCHEMISTRY, AND ENANTIOSELECTIVITY OF 3′,4′‐DIHYDROXYNOMIFENSINE ↗

  ChemInform · 1984
  not yet assessed
• Dopaminergic Benzazepines with Divergent Cardiovascular Profiles ↗

  ACS symposium series · 1983
  not yet assessed
• ChemInform Abstract: 6‐(PHENYLTHIO)‐SUBSTITUTED 2,3,4,5‐TETRAHYDRO‐1H‐3‐BENZAZEPINES, A NOVEL CLASS OF DOPAMINE RECEPTOR ANTAGONISTS AND NEUROLEPTICS ↗

  ChemInform · 1981
  not yet assessed
• 6-(Phenylthio)-substituted 2,3,4,5-tetrahydro-1H-3-benzazepines, a novel class of dopamine receptor antagonists and neuroleptics ↗

  Journal of Medicinal Chemistry · 1980 · PMID 6106062
  not yet assessed